Anesthetic Management for Surgical Gastrostomy in a Patient with Leigh Syndrome

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Anesthetic Management in Pediatric Patient for Percutaneous Endoscopic Gastrostomy with Mitochondrial Myopathy: Leigh Syndrome

Leigh syndrome (LS) is a rare disease mainly affecting the central nervous system due to the abnormalities of mitochondrial energy generation and seen in early childhood with progressive loss of movement, mental abilities, seizures, nystagmus, ophthalmoparesis, optic atrophy, ataxia, dystonia, or respiratory failure. Anesthesia and surgery exacerbate the risks of aspiration, wheezing, and breat...

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Anesthetic management of a pediatric patient with Leigh syndrome.

BACKGROUND AND OBJECTIVES Leigh syndrome (LS) is a rare disease caused by abnormalities of mitochondrial energy generation. The central nervous system is most frequently affected, with psychomotor underdevelopment, seizures, nystagmus, ophthalmoparesis, optic atrophy, ataxia, dystonia, or respiratory failure. Surgical and anesthetic procedures stimulate the tracheal irritability, and could exac...

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Introduction Herein, we describe the interesting case of a 13-year-old female with Kearns-Sayre syndrome (KSS) who underwent a successful T3 ~ L3 posterior spinal instrumentation and fusion (PSIF). KSS is a rare mitochondrial myopathy with only 226 cases reported in published literature as of 1992. It is the result of deletions in mitochondrial DNA and manifests as a triad of: 1) chronic progre...

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Corresponding author: Joon-Ho Lee, M.D., Ph.D., Department of Anesthesiology and Pain Medicine, Bucheon Hospital, Soonchunhyang University, 1174, Jung-dong, Wonmi-gu, Bucheon 420-767, Korea. Tel: 82-32-621-5340, Fax: 82-32-621-5322, E-mail: [email protected] This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativec...

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ژورنال

عنوان ژورنال: Yamaguchi Medical Journal

سال: 2018

ISSN: 0513-1731,1880-4462

DOI: 10.2342/ymj.67.155